Location: US 45 and MS 19, Meridian Reassurance shield after MS 19. Location: US 45 and MS 19, Meridian Immediately after MS 19 we’ll approach Interstates 20 and 59. Location: US 49 and I-20, Meridian Exit for I-20 east and I-59 north to Tuscaloosa, Ala. Location: US 45 and I-20, Meridian Follow 20 west and … Continue reading U.S. Route 45, MS-19 to I-20/I-59